Takara, 635079, iDimerize™ Inducible Heterodimer System (with Tet-On® 3G)

The iDimerize Inducible Heterodimer System (with Tet-On 3G) lets you control the expression levels and heterodimerization of two different proteins of interest, encoded on a single vector, in live cells. The system includes the iDimerize Inducible Heterodimer Vector Set 2, which contains a mammalian bidirectional expression vector (pTRE3G-BI-Het1) that allows simultaneous, doxycycline-dependent expression of two proteins of interest, tagged with the DmrA and DmrC domains, respectively, in Tet-On 3G transactivator-expressing cells. The activity and localization of the resulting DmrA- and DmrC-tagged proteins is controlled by the addition of the A/C Heterodimerizer.