Thermo Fisher, A30091, <i>Silencer</i>™ Select Human Drug Targets siRNA Library (384 well), 1 set (384-well)

Name: Silencer ™ Select Human Drug Targets siRNA Library (384 well), 1 set (384-well)
Brand: Thermo Fisher
SKU: A30091

Format: 384-well Plate, Unit Size: Each

Catalog Number: A30091

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Category

General Purpose Solvents

Pack Size384 wells

TagssiRNA RNAi and RNA Reagents

CollectionsThermo Fisher RNAi & RNA Reagents for Reliable Gene Silencing Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Format: 384-well Plate
Unit Size: Each
• TheSilencer™ Select Human Drug Targets siRNA Library includes genes involved in apoptosis, senescence, nucleic acid binding, autophagy, DNA repair, along with characterized nuclear receptors and other genes that are considered potential targets for therapeutics
• TheSilencerSelect Human Drug Targets siRNA Library contains 23,778 Ambion™SilencerSelect highly potent and chemically-modified siRNAs targeting 7,926 genes for performing RNAi screens against known human drug target genes
• This library was designed using the most up-to-date genome databases, including the NCBI RefSeq database
• It is cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC)
• The library includes gene IDs from Thermo Fisher's Human Druggable Genome and Human Extended Druggable Genome siRNA libraries that are not already in the kinase, phosphatase, protease, ion channel, GPCR or ubiquitin libraries
• TheSilencerSelect siRNAs are designed using Thermo Fisher Scientific’s leading algorithms—along with our novel locked nucleic acid (LNA) chemical modifications
• This helps to help ensure the efficacy, specificity, and potency required for RNAi screening using a comprehensive pre-defined platform for therapeutic discovery
• Superior efficacy – Reduce off target effects by up to 90% due to latest design algorithms and LNA chemical modifications
• Highest efficiency – Perform knockdown studies with 100-fold more potent siRNAs than currently available siRNAs
• Dependable – Achieve faster discoveries via consistency of gene knockdown and reliability of phenotypic results
• Convenient – Reduce data de-convolution and accelerate target validation with our 96- and 384-well arrayed format
• Customizable – Choose the best option for workflow demands, including additional siRNA scales and pooled formats
• Contains 0.25 nmol of each highly potent siRNA, sufficient for at least 500 transfections (at 5 nM siRNA, 100 μL transfection volume)

Specifications

General

For Use With (Application)	RNAi
Product Line	Silencer™Select
Product Type	siRNA Library
Purity	Standard
Quantity	1 set (384-well)
Shipping Condition	Approved for shipment at Room Temperature or on Wet Ice
Format	384-well Plate
RNAi Type	siRNA
Sample Type	DNA
Species	Human
Unit Size	Each

Ordering

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