Wako, 010-26861, Anti TERT, Monoclonal Antibody (TMab-6)

This product is for research use only. Do not administer it to human., TERT (Teromerase ReverseTranscriptase) is one of the subunit of teromerase, which consists of TERT, TERC, dyskerin and more subunits., The mutations in the promoter region of TERT gene have been found in various cancers including diffuse gliomas, and have been demonstrated the importance of the TERT promoter mutations in the classification of diffuse gliomas., Anti TERT, monoclonal antibody (TMab-6) is established against the synthetic peptide of hTERT. This antibody is useful for immunohistochemistry., This product is for laboratory use only ; use in any such application is the responsibility of the users., [Reactivity] Reacts with human TERT, [Species cross reactivity] Human, [Clone No.] TMab-6, [Host] Mouse, [Isotype] IgM·κ, [Concentration] Indicated on the Label., [Formulation] PBS(pH 7.4) containing sodium azide, [Application], Western Blot 1µg/mL-, Immunohistochemistry 1µg/mL-, ELISA 1µg/mL-, *Please optimize the most appropriate concentration for your analysis conditions and samples., [Reference], Masui, K., Komori, T., Kato, Y., Masutomi, K., Ichimura, K., Ogasawara, S., Kaneko, M.K., Oki, H., Suzuki, H., Nitta, M., Maruyama, T., Muragaki, Y., Kawamata, T., Sawada, T. and Shibata, N., "Elevated TERT expression in TERT-wildtype adult diffuse gliomas: Histological evaluation with a novel TERT-specific antibody.", BioMed Research International, Vol. 2018, Article ID 7945845, (2018).