Wako, 012-27443, Anti CTGF Module3, Monoclonal Antibody(3-54)

This product is for research use only. Do not administer it to human.CTGF is a secreted protein of about 38 kDa produced from umbilical veins and vascular endothelial cells. Module 1-4 consists of four parts. Module 1 is called an IGF binding domain, Module 2 is called VWC domain, Module 3 is called TSP-1 domain, Module 4 is called CT domain, and different factors bind to each domain. It is known to be involved in proliferation and differentiation of chondrocytes and intercellular adhesion. This antibody is a mouse monoclonal antibody which recognizes CTGF of Native form established by DNA immunization method and specifically recognizes Module 3 of CTGF., [Antibody subclass] mouse IgG1, [Species crossing] human, mouse, [Experimental adaptation] Neutralization experiment (2.5 μg / mL), [Reference], 1) Nozawa, K.,, et al.: Arthritis Rheum, ., 65, , 6, 1477 (2013)., 2) Miyashita, T.,, et al.: Autoimmunity, ,, 49, , 2, 109 (2016).