Wako, 018-27423, Anti CTGF Module1, Monoclonal Antibody(30D2)

This product is for research use only. Do not administer it to human.CTGF is a secreted protein of about 38 kDa produced from umbilical veins and vascular endothelial cells., Module 1 consists of four parts; Module 1 is IGF binding domain, Module 2 is VWC domain, Module 3 is TSP-1 domain, Module 4 is called CT domain, and different factors are linked to each domain. It is known to be involved in proliferation and differentiation of chondrocytes and intercellular adhesion., This antibody is a mouse monoclonal antibody which recognizes CTGF of Native form established by DNA immunization method and specifically recognizes Module 1 of CTGF., [Antibody subclass] mouse IgG1, [Species cross reactivity] human, mouse, [Experimental adaptation], in vitro neutralization experiment(15ug/mL), ELISA(5ug/mL), in vivo neutralization experiment(10mg/kg), Reference, 1)Nozawa, K., et al.: Arthritis Rheum.65, 6, 1477(2013)., 2)Miyashita, T., Autoimmunity. 49, 2,109(2016).