Wako, 068-01663, 10% Formalin Neutral Buffer Solution

Fixation means a process by which when observing microscopically the ecological or pathological state of a tissue specimen taken from a dead or live body, the tissue specimen is preserved in as "intact" a state as possible.The objectives are to:- Stabilize the main constituent protein of the tissue specimen as fast as possible to stop autolysis- Minimize the degeneration and deformation of the tissue specimen caused by the effects of chemicals and heat during the subsequent specimen preparation process.——, Formalin solution is used in large quantities as a routine fixative in the preparation of tissue specimens for light microscopic observation. Formalin is decomposed to produce formic acid, which may affect some tissues. This neutral buffered formalin is adjusted to pH 7.4 approximately by the addition of sodium phosphate to formalin to eliminate the effect of acid on tissues.