Wako, 295-97201, FM Fix (s)

Tissue fixation is an important procedure to protect biological specimens from degradation due to autolysis and decay, ensuring stable preservation of proteins and other components within the tissues. Formalin fixation is widely used in research and pathology, including microscopy specimen preparation, however, it can affect the steric structure and antigenicity of some proteins, leading to deterioration in staining quality and other properties., FM Fix (L) is a fixative that has superior tissue staining properties while retaining tissue morphology and three-dimensional structure. It helps to maintain the three-dimensional structure of proteins even after tissue fixation, enabling the stable detection of antigens such as complements. In addition, it is characterized by minimal reduction of fluorescence protein signals such as GFP, making it suitable for tissue transparency techniques., FM Fix(s) is a fixative optimized for small tissues such as needle biopsies and tissues with good permeability, while maintaining the fixative characteristics of FM Fix(L).