Cytiva
25 mm (0.5") TC 9.5 mm (0.375") barb
SKU · 56410980
Loading…
Bioprocess filtration is essential for removing impurities and ensuring product quality throughout biopharmaceutical manufacturing. Cytiva’s bioprocess filtration portfolio includes tangential flow filtration (TFF), normal flow filtration, and depth filtration solutions designed for applications such as cell harvest, clarification, concentration, and sterile filtration in research and production environments.
Tangential flow filtration (TFF) is a highly efficient technology used for concentrating and diafiltering biological samples during bioprocessing. Unlike traditional direct flow methods, TFF directs liquid parallel to the membrane surface, minimizing fouling and allowing for consistent, scalable filtration performance.
Cytiva offers a comprehensive range of TFF systems, including both single-use and reusable configurations, to support applications from laboratory-scale research to large-scale production. These systems are ideal for protein concentration, buffer exchange, and cell harvest, enabling high product recovery and process flexibility.
By integrating advanced TFF modules and automated control platforms, Cytiva’s bioprocess filtration solutions help you streamline workflows, maintain product integrity, and scale processes efficiently across different development stages.
Normal flow filtration (NFF), also known as direct flow filtration, is widely used for removing particles, cell debris, and microorganisms during bioprocess clarification steps. By forcing liquid directly through the membrane, NFF provides reliable and consistent retention of contaminants, supporting downstream process purity and efficiency.
Depth filtration utilizes multi-layered filter media to capture a broad range of particulate impurities, including fine debris and colloidal material. This method is especially effective as a primary clarification step before sterile filtration or chromatography, extending the lifespan of downstream filters and improving overall process yield.
Cytiva offers both normal flow and depth filtration solutions engineered for high throughput, scalability, and compatibility with a variety of bioprocessing applications. These technologies help you achieve robust viral clearance, efficient particle removal, and streamlined process integration from lab to manufacturing scale.
Sterile filtration is a critical step in bioprocessing, ensuring product safety and regulatory compliance by effectively removing bacteria and other microorganisms from final products. Cytiva provides a comprehensive range of sterile filters designed for high throughput, low protein binding, and robust microbial control, supporting both bioburden reduction and final sterilizing filtration.
Key advantages of Cytiva sterile filtration solutions include:
With validated filter membranes and proven process compatibility, Cytiva’s sterile filtration products enable you to meet strict regulatory standards while maximizing process efficiency.
Efficient cell harvest, concentration, and diafiltration are essential for maximizing product yield and purity in bioprocess workflows. Cytiva’s advanced filtration systems enable you to separate cells, concentrate target biomolecules, and exchange buffer solutions with high efficiency and scalability.
Key benefits of Cytiva solutions for these applications include:
By leveraging Cytiva’s filtration technologies, you can streamline your cell harvest and purification steps, ensuring consistent process outcomes and reliable scale-up.
Cytiva’s bioprocess filtration solutions are designed to address the evolving technical challenges of modern biomanufacturing—from process development to commercial production. Leveraging advanced membrane engineering and system-level integration, Cytiva enables you to achieve robust, reproducible, and scalable filtration outcomes across upstream and downstream workflows.
Advanced Membrane Technologies
Cytiva offers a comprehensive selection of membrane materials, including polyethersulfone (PES), cellulose, and polypropylene, each tailored for specific bioprocess needs such as high protein recovery, low extractables, and chemical compatibility. Multi-layered depth filter media are engineered for efficient clarification and extended filter life, supporting challenging feed streams and high particle loads.
Versatile System Compatibility
You can choose from single-use (disposable) or reusable filtration formats, with standardized cartridge, capsule, and module designs. This flexibility supports rapid changeover, closed-system processing, and alignment with GMP-compliant manufacturing, minimizing cross-contamination risks and streamlining validation.
Integrated Automation and Process Control
Cytiva filtration platforms are optimized for seamless integration with automated control systems, enabling real-time monitoring of critical parameters such as pressure, flow rate, and transmembrane pressure (TMP). Integrated data acquisition supports process traceability, consistent batch performance, and digital quality management in regulated environments.
Scalable Solutions for All Phases
From bench-scale development to full-scale production, Cytiva’s filtration systems are engineered for linear scalability. You benefit from matched performance across scales, enabling direct process transfer and reducing the risk of bottlenecks during process scale-up or tech transfer.
Regulatory Compliance and Validation Support
Cytiva filtration products are rigorously validated to meet global regulatory standards, including USP, EP, and FDA requirements. Comprehensive documentation and application support simplify regulatory submissions and facilitate process qualification.
By combining innovative materials science with intelligent system design and deep industry expertise, Cytiva empowers you to optimize bioprocess yields, ensure batch-to-batch consistency, and accelerate time to market in a highly competitive regulatory landscape.
Choosing the optimal filtration solution is critical for achieving consistent product quality and efficient bioprocessing. Cytiva provides a diverse portfolio of filters tailored to different process volumes, pore sizes, and end-use requirements. When selecting a filter, you should evaluate the following key factors:
By systematically addressing these criteria, you can identify the most suitable Cytiva filtration solution to optimize process efficiency, product yield, and regulatory alignment at every stage of biomanufacturing.
| Category | Product Name (SKU) | Typical Application |
|---|---|---|
| Depth Filtration | Stax™ Disposable Depth Filter Capsule (SKU: 7008601) | High‑turbidity feed primary clarification (iright.com) |
| Depth Filtration | Profile™ II Depth Filter Capsule (SKU: NP8Y003P1G) | Broad‑range particulate removal |
| Depth Filtration | Supracap™ 50 Depth Filter Capsule (SKU: SC050P1500) | Mid‑scale clarification |
| Tangential Flow Filtration (TFF) | UniFlux™ TFF System (SKU: 29010658) | Pilot to production-scale concentration & diafiltration |
| Normal Flow / Sterile Filtration | Supor® Prime Capsule Filter (SKU: DC3ASFP2LSFT) | Sterile filtration with high throughput |
| Normal Flow / Sterile Filtration | Fluorodyne™ II DFL Capsule (SKU: KA1DFLP2G) | 0.2 µm sterilizing-grade liquid filtration |
Filter this collection by brand or tags.