Cytiva Cell Therapy Solutions – GMP Cell Therapy Manufacturing Platform

When you choose Cytiva Cell Therapy Solutions, you access an integrated portfolio of industry‑leading systems designed for GMP cell therapy manufacturing. From process development to commercial scale, Cytiva delivers automated, closed‑system platforms that streamline every stage of your cell therapy workflow.

Xuri™ Cell Expansion Systems provide scalable bioreactor solutions for robust cell expansion, ensuring consistent growth and high cell viability.

Sepax™ C‑Pro and Sefia™ Cell Processing Systems enable automated cell separation, washing, and formulation with flexible protocols—minimizing manual handling and cross‑contamination risks.

For advanced cryopreservation and logistics, VIA Freeze™ and VIA Thaw™ systems offer precise, controlled freezing and thawing of valuable cell therapies, helping you maintain product quality throughout the supply chain.

At every stage, the modular FlexFactory™ Cell Therapy Platform supports seamless scale‑up and technology transfer, integrating hardware, software, and single‑use consumables for a true end‑to‑end solution.

With Cytiva’s comprehensive cell therapy manufacturing systems, you’re equipped to accelerate clinical development, ensure GMP compliance, and confidently bring cell therapies to patients.

Key Features: GMP‑Compliant Closed System Automation

With Cytiva Cell Therapy Solutions, you benefit from advanced GMP-compliant automation designed specifically for modern cell therapy manufacturing. Each platform delivers a fully closed, integrated environment that minimizes manual intervention and supports consistent, high-quality results—helping you meet the rigorous standards of clinical and commercial cell therapy production.

Core Features and Advantages:

• Fully Automated Processing: Automated cell separation, expansion, formulation, and cryopreservation reduce hands-on steps, boost reproducibility, and streamline your workflows.
• Closed-System Operation: All processes are performed in closed, single-use systems to prevent contamination, protect product integrity, and ensure operator safety.
• GMP Compliance: Every platform is engineered to meet global GMP standards, supporting regulatory submissions and commercial scalability.
• Reduced Cross-Contamination Risk: Seamless, single-use workflows and minimal open handling sharply lower the risk of cross-contamination.
• Consistent, Scalable Results: Precision-controlled environments and standardized protocols drive process consistency from research through large-scale manufacturing.

By leveraging Cytiva’s closed system automation, you gain greater efficiency, traceability, and confidence in every batch of cell therapy you manufacture.

Consumables & Media: Single‑Use Kits for Cell Therapy

To support your cell therapy processes from start to finish, Cytiva offers a full portfolio of high-quality, single-use consumables and cell culture media. These solutions are engineered for seamless integration with Cytiva’s automated platforms, helping you maximize workflow efficiency and maintain strict control over product safety and quality.

Key Consumables and Media Solutions:

• Single-Use Bags and Assemblies: Sterile, closed-system bags designed for safe cell collection, expansion, formulation, and cryopreservation, reducing the risk of contamination and streamlining changeover.
• Cell Therapy Culture Media: Specialized media and supplements, optimized for different cell types and applications, ensure robust cell growth, viability, and reproducibility.
• Growth Factors & Reagents: High-purity growth factors and essential reagents support the expansion and differentiation of target cell populations.
• Single-Use Kits and Tubing Sets: Ready-to-use kits and tubing assemblies compatible with Xuri™, Sepax™, and Sefia™ systems simplify set-up and minimize manual handling.
• Customizable Solutions: Configurable consumable packages tailored to your specific clinical or commercial needs, ensuring process flexibility as you scale.

By utilizing Cytiva’s single-use cell therapy consumables and media, you can enhance operational safety, drive lot-to-lot consistency, and accelerate the development of innovative cell therapies.

Digital Control: Chronicle™ Quality & Traceability Software

As your cell therapy workflows become more advanced, maintaining rigorous quality standards and full process traceability is critical for GMP compliance and operational excellence. Cytiva’s Chronicle™ software delivers a comprehensive digital solution designed specifically for cell therapy manufacturing, seamlessly connecting your equipment, documentation, and quality systems.

With Chronicle™ software, you can:

• Digitize Batch Records & SOP Management: Replace paper-based records with secure, searchable electronic batch records and SOPs, making compliance and audits easier than ever.
• Enable Real-Time Process Monitoring: Monitor critical process parameters across your cell therapy manufacturing in real time, ensuring immediate response to deviations.
• Enhance Traceability: Achieve full end-to-end traceability of materials, operators, and process steps—supporting GMP requirements and simplifying investigations.
• Automate Quality Control Workflows: Integrate quality data directly into your digital records, reducing manual data entry and potential for human error.
• Improve Data Integrity & Security: Benefit from robust data protection, controlled user access, and reliable backup solutions for peace of mind.

By integrating Chronicle™ software into your Cytiva cell therapy platform, you empower your team to drive efficiency, maintain compliance, and ensure consistent quality—batch after batch.

Featured Products & SKUs: Compare Leading Cytiva Cell Therapy Systems

Choose from Cytiva’s top platforms tailored to each stage of your cell therapy workflow. The table below helps you compare key systems, including SKUs, compatible cell types, scale, and core specifications to streamline your selection process.

Product	SKU / Part No.	Workflow Stage	Core Specs / Details
Xuri™ Cell Expansion System W25	29064568 (base unit); 29064571 (pump)	Cell expansion (2–25 L perfusion)	Closed single-use Cellbag bioreactors, up to >10 × 10⁶ cells/mL, controlled pH/DO via UNICORN™
Sepax™ C‑Pro Cell Processing System	29264741 (instrument); consumables CT‑49.1, CT‑60.1, CT‑90.1 kits	Cell separation, washing, formulation	Automated closed workflows (centrifuge up to 220 mL); supports bead wash, spinoculation, dilution
VIA Freeze™ Controlled-Rate Freezer	(check Cytiva catalog)	Cryopreservation	Controlled freezing profiles in closed bags ensuring cell viability
VIA Thaw™ Automated Thawing System	(check Cytiva catalog)	Thawing	Automated, reproducible thawing in closed format to maintain cell integrity
FlexFactory™ Cell Therapy Platform	Customizable configuration	End-to-end manufacturing	Modular GMP platform integrating expansion, processing, freezing, and analytics for scalable production