Merck ISOTEC Stable Isotope‑Labeled Compounds Collection

Merck’s ISOTEC™ Stable Isotopes represent the benchmark for reliability and innovation in isotope-labeled compounds, supporting cutting-edge research across the life sciences, pharmaceutical development, clinical diagnostics, and advanced materials. As a global leader in the field, Merck delivers unmatched purity, batch-to-batch consistency, and GMP-certified products to laboratories and production environments worldwide. With decades of expertise, the ISOTEC™ portfolio empowers you to drive discovery, gain precise analytical insights, and confidently meet regulatory requirements—whether your focus is basic research or the most advanced clinical applications.

Applications in Metabolomics, Proteomics & MRI/MRS

Merck ISOTEC™ stable isotope-labeled compounds are integral to some of the most dynamic and high-impact research fields today.

Stable isotopes such as ^13C, ^15N, ^2H (deuterium), and ^18O enable scientists to design highly accurate metabolic flux studies, unlock protein function through advanced proteomics, and develop sensitive diagnostic assays for clinical and industrial use. These reagents serve as tracers, standards, and references, facilitating targeted, quantitative, and reproducible analysis in complex biological and chemical systems.

Major Application Areas:

Application Area	Typical Use Cases
Metabolomics	Metabolic flux analysis, quantifying metabolites, tracing pathways
Proteomics	Protein labeling, quantification, dynamic turnover studies
NMR / MRS	Structure elucidation, kinetic studies, in vivo imaging
Clinical Diagnostics	Urea breath tests, diagnostic isotope standards, biomarker discovery
Pharmaceutical Research	ADME studies, drug metabolism, pharmacokinetics, formulation
Food & Environmental Safety	Authenticity testing, contamination tracing, residue analysis

By leveraging ISOTEC™ stable isotopes, you gain the flexibility to approach complex biological questions with precision, reliability, and regulatory compliance.

Isotope Types & Product Categories: ^2H, ^13C, ^15N, ^18O

Building on Merck’s heritage of innovation and technical excellence, the ISOTEC™ collection covers a broad array of stable isotope elements and compound classes. Each product is engineered for superior isotopic enrichment and chemical purity, ensuring optimal performance in demanding workflows.

Main Stable Isotope Elements:

• ^2H (Deuterium): Essential for metabolic tracing, kinetic isotope effects, and NMR solvent standards.
• ^13C: Used extensively in metabolic flux analysis, protein labeling, and as internal standards for quantitative mass spectrometry.
• ^15N: Preferred for NMR studies of proteins and nucleic acids, as well as tracer studies in metabolic and ecological research.
• ^18O: Utilized in enzymatic studies, water flux experiments, and as labeling agents in mass spectrometry.

Key Product Categories:

• Amino Acids: ^13C- and ^15N-labeled glycine, leucine, glutamine, and others for protein structure and turnover studies.
• Carbohydrates & Sugars: ^13C-labeled glucose, fructose, galactose—critical for metabolic profiling.
• Organic Acids: Labeled lactate, pyruvate, acetate—vital for energy metabolism research.
• Solvents & Small Molecules: Deuterated solvents (D2O, CDCl3) and ^13C-methanol for NMR and analytical chemistry.
• Gases: ^13CO2, ^15N2, ^18O2 for respiratory and environmental applications.
• Custom Compounds: Tailored isotope-labeled chemicals to fit unique experimental requirements.

Each ISOTEC™ product undergoes rigorous quality control, with Certificate of Analysis (COA) and isotopic enrichment data provided to support your validation and regulatory documentation needs.

Featured Products & Top Merck SKU List

To help you select the optimal reagent for your workflow, below are some of the most in-demand Merck ISOTEC™ stable isotope-labeled products. All SKUs and specifications are directly matched with Merck’s official catalog. For the most accurate and complete list, always refer to the latest Merck official documentation.

SKU	Product Name	Isotope	Purity/Enrichment	Typical Use
389374	L-Glutamic acid, [U-^13C5]	^13C	≥ 99%	Metabolomics, protein labeling
492014	D-Glucose, [U-^13C6]	^13C	≥ 99%	Metabolic flux analysis
486925	Urea, [^13C,^15N2]	^13C/^15N	≥ 99%	Clinical urea breath test
151882	Methanol-d4	^2H	≥ 99.8% (D)	NMR solvent
254839	Glycine, [^15N]	^15N	≥ 98%	NMR, metabolic studies
364368	Water, H2^18O	^18O	≥ 98% (O)	Enzyme studies, isotope tracing

Why Choose Merck Stable Isotope Standards

Selecting Merck ISOTEC™ means you benefit from industry-leading quality, technical expertise, and responsive support. Every stable isotope-labeled compound is manufactured to the highest standards, offering:

• Exceptional Isotopic Purity: Minimized background signal and enhanced analytical reliability.
• Batch-to-Batch Consistency: Robust quality control, with each lot supplied with a detailed Certificate of Analysis.
• GMP & Custom Solutions: GMP-certified options available for regulated and clinical workflows; custom syntheses for specialized research.
• Global Distribution & Support: Access to technical assistance, regulatory documentation, and rapid delivery to your lab—no matter where you are.
• Regulatory Compliance: Full documentation and traceability to support your audits and reporting requirements.

Whether you are advancing fundamental science, developing diagnostic tools, or scaling pharmaceutical manufacturing, Merck ISOTEC™ offers the confidence and flexibility you need.

Order Now: Trusted Distributor Iright & Quote Request

Ready to optimize your research with the world’s leading stable isotope standards? As an authorized distributor, Iright provides reliable access to the complete Merck ISOTEC™ catalog, backed by expert support and fast, secure delivery.

For detailed quotations, bulk order inquiries, or technical questions, contact the Iright team today. We are committed to providing personalized assistance to help you select the right stable isotope products for your scientific goals.