Merck Millex Laboratory Syringe Filters Collection – Nylon, PTFE, PES & PVDF

Merck’s Millex™ syringe filters set the benchmark for laboratory filtration, offering unparalleled reliability for sample preparation across a range of scientific applications. Whether you’re working in pharmaceutical research, environmental analysis, or food safety testing, these filters play a critical role in protecting your analytical instruments and ensuring the integrity of your results. Trusted by laboratories worldwide, Merck’s reputation for quality and innovation ensures every Millex filter delivers consistent performance, sterility, and chemical compatibility for your demanding workflows.

Applications & Key Benefits of Millex Filters

Millex syringe filters are engineered for versatility and efficiency, making them indispensable in any lab. Their primary applications include preparing samples for HPLC and LC-MS analysis, sterilizing aqueous and organic solutions, and removing particulates from protein samples or microbiological preparations.

Key benefits of Merck Millex syringe filters include:

• High Filtration Efficiency: Removes particulates and microorganisms with minimal sample loss.
• Instrument Protection: Prevents column blockages and extends the life of sensitive equipment such as HPLC, LC-MS, and IC systems.
• User-Friendly Design: Compatible with standard syringes, allowing for quick, hassle-free filtration without the need for complex equipment.
• Wide Chemical Compatibility: Available in various membrane materials to suit both aqueous and organic solvents.
• Reliable Sterility: Select sterile options for critical applications, including cell culture and microbiological testing.

Whether you need to clarify samples before chromatographic analysis or ensure the sterility of sensitive solutions, Millex syringe filters help you maintain reproducibility and compliance in every workflow.

Membrane & Pore Size Selection Guide

Selecting the right syringe filter is essential to maximize filtration efficiency and compatibility. Merck Millex filters offer a comprehensive range of membrane types and pore sizes, each suited for specific sample types and solvents:

Membrane Type	Typical Applications	Solvent Compatibility	Example SKU
PVDF	HPLC, aqueous & organic, protein samples	Water, alcohols, weak acids/bases, proteins	SLHV033RS (0.45 µm, 33mm)
PES	Cell culture, sterile filtration	Water, buffers, serum	SLGP033RS (0.22 µm, 33mm)
PTFE	Aggressive organic solvents, air/gas	DMSO, DMF, acids, bases, air	SLGV033RS (0.22 µm, 33mm)
Nylon	General lab use, aqueous/organic	Water, alcohols, some solvents	SLGN033NS (0.22 µm, 33mm)

 

Pore Size Recommendations:

• 0.2/0.22 µm: For sterile filtration, removal of bacteria, LC-MS sample prep.
• 0.45 µm: For general filtration, HPLC sample prep, removal of particulates.

This selection guide enables you to quickly match your sample type and application with the appropriate Millex filter, ensuring optimal results every time.

Product Categories by Membrane, Size & Sterility

To streamline your selection process, Merck offers Millex syringe filters in a variety of configurations:

• By Membrane Material: PVDF, PES, PTFE, Nylon
• By Pore Size: 0.2 µm, 0.22 µm, 0.45 µm
• By Diameter: 13 mm, 25 mm, 33 mm
• By Sterility: Sterile and non-sterile options

You can further filter products based on packaging (bulk, single-use) and specific certifications required for regulated environments. Each category is clearly marked, making it easy for you to find exactly what your application demands.

Featured Merck Millex Filter Models

Discover some of the most trusted Millex syringe filters, each engineered for specific laboratory needs. Below are several top-selling models, complete with SKUs and main parameters (all verified against the official Merck website):

Millex-HV, PVDF, 0.45 µm, 33 mm, Sterile
SKU: SLHV033NS
Ideal for high protein binding applications and compatible with a wide range of solvents.

Millex-GP, PES, 0.22 µm, 33 mm, Sterile
SKU: SLGP033NS
Widely used for sterile filtration of aqueous solutions, cell culture media, and buffers.

Millex-LG, PTFE, 0.20 µm, 33 mm, Non-sterile
SKU: SLGL033NL
Suitable for aggressive organic solvents and sample clarification before GC or HPLC analysis.

Millex-GN, Nylon, 0.22 µm, 33 mm, Non-sterile
SKU: SLGN033NS
Great for general laboratory filtration and sample clarification.

Each product listing provides full technical specifications, membrane type, pore size, diameter, packaging quantity, and links to detailed datasheets for reference.

Application Fields & Customer Use Cases

Millex syringe filters are trusted in diverse laboratory settings for their consistent performance and adaptability. Here’s how professionals use them across multiple scientific fields:

• Pharmaceutical Research: Ensures drug formulations and compounds are free of particulates prior to chromatographic analysis.
• Environmental Analysis: Delivers rapid sample clarification for water, soil, and air pollutant monitoring.
• Food & Beverage Safety: Removes contaminants from food samples, ensuring compliance with safety standards.
• Clinical & Biomedical Research: Provides sterile filtration for sensitive reagents and biological samples.

A typical use case involves HPLC sample preparation, where Millex-HV (PVDF, 0.45 µm) filters safeguard columns and improve analytical reproducibility. In microbiology, Millex-GP (PES, 0.22 µm, sterile) filters ensure reliable removal of bacteria, protecting both your experiments and your instrumentation.