Beckman Coulter, 354511, 11 mm Diameter Metal Tube Adapter Plate
Catalog Number: 354511
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Category
| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | CD304-Fc Fusion protein |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. |
| Excitation Laser | Blue Laser (488 nm) |
| RRID | AB_2562318 (BioLegend Cat. No. 354511) AB_2562319 (BioLegend Cat. No. 354512) |
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| Structure |
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| Type I transmembrane protein, 140 kD, 2 complement binding domains (CUB), 2 coagulation factor V/VIII homology domains (FV/FVIII), one meprin, A5, receptor tyrosine phosphatase domain (MAM) |
| Distribution | Plasmacytoid dendritic cells, thymocytes, subset of follicular helper T cells (TFH), endothelial cells, neurons, some carcinomas |
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| Function | Angiogenesis, neuronal development, tumor metastasis |
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| Ligand/Receptor | VEGF165, semaphorin-3A |
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| Cell Type | Dendritic cells, Endothelial cells, Neurons, Tfh, Thymocytes |
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| Biology Area | Angiogenesis, Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroscience, Synaptic Biology |
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| Molecular Family | Adhesion Molecules, CD Molecules |
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| Antigen References | 1. Mizui M and Kikutani H. 2008. Immunity 28:302. 2. Hamerlik P, et al. 2012. J. Exp. Med. 209:507. 3. Karjalainen K, et al. 2011. Blood 117:920. 4. Lepelletier Y, et al. 2007. P. Natl. Acad. Sci. USA 104:5545. |
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| Gene ID | 8829 |
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| UniProt | View information about CD304 on UniProt.org |
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| Clone | 12C2 |
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| Regulatory Status | RUO |
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| Other Names | BDCA-4 |
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| Isotype | Mouse IgG2a, κ |
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