Beckman Coulter, 367101, 16 mm Diameter Aluminum Tube Spacer, Quantity of One
Catalog Number: 367101
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| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | Purified human peripheral blood monocytes. |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Preparation | The antibody was purified by affinity chromatography. |
| Concentration | 0.5 mg/ml |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Application References(PubMed link indicates BioLegend citation) | Fridlender ZG, et al. 1999. Hum. Immunol. 11:1028. Devitt A, et al. 1998. Nature 6675:505. |
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| Product Citations |
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| Huang L, et al. 2020. JCI Insight. 5:00. PubMed Mann ER, et al. 2020. Sci Immunol. :5. PubMed Heesters BA, et al. 2021. J Exp Med. 218:. PubMed Priyanto H, et al. 2021. J Clin Tuberc Other Mycobact Dis. 22:100214. PubMed Bashth OS, et al. 2020. Biomater Sci. 4.128472222. PubMed Ferdosi SR, et al. 2019. Nat Commun. 1.695833333. PubMed Azari S, et al. 2021. MBio. 12:e0184921. PubMed O'Boyle KC, et al. 2020. Methods Mol Biol. 2111:1. PubMed Farhadian SF, et al. 2022. JCI Insight. 7:. PubMed Boulanger MD, et al. 2022. PLoS One. 17:e0269316. PubMed Chen W, Pilling D, and Gomer R 2017. BMC Immunol. . 10.1186/s12865-017-0230-z. PubMed |
| RRID | AB_2565627 (BioLegend Cat. No. 367101) AB_2565628 (BioLegend Cat. No. 367102) |
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| Structure | GPI-linked membrane glycoprotein. |
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| Distribution | Monocytes, macrophages, dendritic cells, and granulocytes. |
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| Function | LPS receptor, clearance of Gram-negative pathogens. |
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| Interaction | LPS. |
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| Ligand/Receptor | LPS. |
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| Cell Type | Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils |
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| Biology Area | Cell Biology, Immunology, Neuroinflammation, Neuroscience |
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| Molecular Family | Adhesion Molecules, CD Molecules |
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| Antigen References | Stocks SC, et al. 1990. Biochem. J. 268:275. Wright SD, et al. 1990. Science 4975:1431. |
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| Gene ID | 929 |
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| UniProt | View information about CD14 on UniProt.org |
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| Clone | 63D3 |
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| Regulatory Status | RUO |
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| Other Names | Monocyte differentiation antigen CD14, myeloid cell-specific leucine-rich glycoprotein, LPS receptor |
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| Isotype | Mouse IgG1, κ |
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