Beckman Coulter, 368910, 17mm Diameter Adapter Assembly Tube, Quantity of Two
Catalog Number: 368910
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| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | Human GPR183-transfected cells |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA). |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
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| Recommended Usage |
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| Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.Learn more about Brilliant Violet™. This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. |
| Excitation Laser | Violet Laser (405 nm) |
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| Product Citations | Bohrer AC, et al. 2022. Cell Rep. 40:111144. PubMed |
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| RRID | AB_2632942 (BioLegend Cat. No. 368909) AB_2632943 (BioLegend Cat. No. 368910) |
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| Structure | Member of the rhodopsin-like subfamily of 7TM receptors and forms homo- and heterodimers. |
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| Distribution | Naive B cells, subset of T cells, monocytes and macrophages |
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| Function | Chemotactic receptor that regulates B cell trafficking within lymphoid follicles. |
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| Ligand/Receptor | 7α, 25-dihydroxycholesterol |
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| Cell Type | B cells, Macrophages, Monocytes, T cells |
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| Biology Area | Cell Biology, Immunology, Innate Immunity |
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| Molecular Family | Cytokine/Chemokine Receptors, Steroid Receptors/Nuclear Receptors |
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| Antigen References | 1. Preuss I, et al. 2014. Biochem. Biophys. Res. Commun. 446:663. 2. Barroso R, et al. 2012. FASEB J. 26:4841. 3. Hannedouche S, et al. 2011. Nature. 475:524. 4. Benned-Jensen T, et al. 2011. J. Biol. Chem. 286:29292. |
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| Gene ID | 1880 |
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| UniProt | View information about GPR183 on UniProt.org |
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| Clone | SA313E4 |
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| Regulatory Status | RUO |
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| Other Names | EBI2 |
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| Isotype | Mouse IgG2a, κ |
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