Bio-Rad, 134001, Collagen IV antibody
Size: 0.2 mg, Goat anti Human Collagen IV
Catalog Number: 134001
Send an RFQ.
Category
Pack Size0.2 mg
Loading…
| Verified Reactivity | Mouse |
|---|---|
| Antibody Type | Monoclonal |
| Host Species | Rat |
| Immunogen | mTim-3 protein/Freund adjuvant |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Preparation | The antibody was purified by affinity chromatography. |
| Concentration | 0.5 mg/ml |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Application Notes | Clone B8.2C12 only binds to the BALB/c allele of Tim-3. |
| Application References(PubMed link indicates BioLegend citation) | del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:
Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.
| Product Citations |
|---|
| Li H, et al. 2022. Cancer Cell. 40:36. PubMed Oba T, et al. 2021. J Immunother Cancer. 9:. PubMed Jing W, et al. 2017. J Immunother Cancer. 5:51. PubMed Zhang Y, et al. 2020. Mol Med Rep. 22:534. PubMed Hongo D, et al. 2012. Blood. 119:1581. PubMed Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed Cané S, et al. 2021. J Immunother Cancer. 9:. PubMed |
| RRID | AB_1626128 (BioLegend Cat. No. 134002) |
|---|
| Structure | Transmembrane protein containing immunoglobulin domain and mucin-like domain. It can exist as a soluble form lacking mucin and transmembrane domains. |
|---|
| Distribution | Expressed on activated Th1 lymphocytes, CD11b+ macrophages, and dendritic cells. |
|---|
| Function | Play a role in regulating macrophage activation, T cell apoptosis and immune tolerance. |
|---|
| Ligand/Receptor | Galectin -9 |
|---|
| Cell Type | Dendritic cells, Macrophages, Th1 |
|---|
| Biology Area | Immunology, Inhibitory Molecules |
|---|
| Molecular Family | CD Molecules, Immune Checkpoint Receptors |
|---|
| Antigen References | 1. Sabatos CA, et al. 2003. Nat. Immunol. 4:1102 2. Kuchroo VK, et al. 2003. Nat. Rev. Immunol. 3:454 3. Mooney L, et al. 2002. Nature. 415:536 4. Rodriguez-Manzanet R, et al. 2009. Immunol. Rev. 229(1):259 |
|---|
| Gene ID | 171285 |
|---|
| UniProt | View information about CD366 on UniProt.org |
|---|
| Clone | B8.2C12 |
|---|
| Regulatory Status | RUO |
|---|
| Other Names | T cell immunoglobulin and mucin domain containing protein 3, hepatitis virus cellular receptor 2, CD366 |
|---|
| Isotype | Rat IgG1, κ |
|---|
