Bio-Rad, 4520-5306, Alpha Fetoprotein antibody | 2I9/2 (166)

Mouse anti Human alpha fetoprotein antibody, clone 219/2 recognizes alpha fetoprotein (AFP), a member of the albuminoid superfamily. It is a ~68 kDa plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. It binds and transports various ligands such as bilirubin, fatty acids, steroids, heavy metals and various drugs. After birth, plasma levels drop to trace amounts in healthy adults Elevated AFP levels are indicative of certain cancers, particularly hepatocellular carcinoma, cancer of the testes or ovaries or a malignant teratoma. During pregnancy increased levels of AFP may indicate neural tube defects such as spina bifida, while decreased levels could indicate Down's syndrome. Mouse anti Human alpha fetoprotein antibody, clone 219/2 does not cross-react with human albumin and other human serum proteins.

Storage Information
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.