Bio-Rad, AHP3019, SARS-CoV-2 Envelope antibody

Rabbit anti SARS-CoV-2 envelope antibody recognizes envelope small membrane protein, also known as sM protein and E. Human coronaviruses are pathogens that can cause severe respiratory tract infections. SARS-CoV-2 is a novel human coronavirus characterized in 2020, and causes "coronavirus disease 2019" or "COVID-19" (Xu et al. 2020). The four main structural proteins of SARS-CoV-2 are the spike (S) glycoprotein, the membrane (M) matrix protein, the nucleocapsid (N) protein, and the envelope (E) protein (Duart et al. 2020). The envelope protein plays a role in compromising the integrity of host membranes and forming membranous compartments in which the virus to replicate (Mukherjee et al. 2020). It forms a homopentameric cation channel which mediates the budding and release of progeny viruses and activates the host inflammasome. Deletion of the envelope protein attenuates some coronaviruses, and the envelope protein has been suggested as a potential drug and vaccine target (Mandala et al. 2020).

Storage Information
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.