Bio-Rad, AHP3044, Histone H2A.J antibody

Rabbit anti Human histone H2A.J antibody recognizes histone H2A.J. Histone H2A.J is a 16 kDa variant of the H2A histone. Histones are nuclear proteins that regulate the nucleosome structure of the chromosomal fibres in eukaryotic cells. Nucleosomes are the smallest subunit of chromatin and are made up of 146 bp of DNA wrapped around an octamer comprised of pairs of the four core histones (H2A, H2B, H3, and H4) ( Smith, 1991 ). Histone H2A.J may be linked to senescence and upregulation of the expression of inflammatory genes. Histone H2A.J may therefore play a role in chronic inflammation and age-related diseases ( Takana et al . 2020 ).

Storage Information
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.