Bio-Rad, AHP3069, Histone H4 antibody

Rabbit anti Human histone H4 antibody recognizes histone H4. Histone H4 is one of the four core histones that make up the nucleosome core particle. Nucleosomes are the smallest subunit of chromatin and are made up of 146 bp of DNA wrapped around an octamer comprised of pairs of the four core histones (H2A, H2B, H3, and H4) ( Smith, 1991 ). Histone H4 is important for the regulation of the structure and function of chromatin. The sequence variants and variable modification states of histone H4 are thought to play a role in both long-term and short-term regulation of genes ( Huang et al . 2005 ) ( Taylor et al . 2013 ).

Storage Information
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.