Bio-Rad, AHP3079, JMJD6 antibody

Rabbit anti Human JMJD6 antibody recognizes bifunctional arginine demethylase and lysyl-hydroxylase JMJD6. JMJD6 is a member of the alpha-ketoglutarate-dependent hydroxylase superfamily located in the nucleus of eukaryotic cells ( Vandivier et al . 2002 ). JMJD6 plays a role in phagocytosis of apoptotic cells and may function as protein hydroxylase or a histone demethylase and play a role in angiogenesis ( Boeckel et al . 2011 ). Aberrant levels of JMJD6 have also been observed in some breast cancers and may be associated with increased tumor aggressiveness and metastasis ( Aprelikova et al . 2016 ).

Storage Information
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.