Bio-Rad, AHP3082, KMT2E antibody

Rabbit anti Human KMT2E antibody recognizes lysine methyltransferase 2E, otherwise known as MLL5. KMT2E is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family of proteins, a group of proteins that are homologous to the evolutionary conserved trithorax group crucial for the regulation of homeotic gene (HOX) expression and embryonic development ( Zhang et al . 2017 ). Aberrant levels of KMT2E have been shown to inhibit cell cycle progression. Mutations in the KMT2E gene have also been associated with neurological disorders such epilepsy and autism as well as abnormalities in gastrointestinal function ( O’Donnell-Luria et al . 2019 ).

Storage Information
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.