Bio-Rad, VMA00910, BCLAF1 antibody | AB02/2F2

Mouse anti BCLAF1 antibody recognizes Bcl-2-associated transcription factor 1, also known as BCLF1. BCLAF1 is a transcription factor involved with multiple processes including apoptosis, T-cell activation, lung development, and angiogenesis ( Wen et al. 2018 ). BCLAF1 has been reported to act as both a tumor suppressor and an oncogene, and so its role in carcinogenesis is not clear, but aberrant alternative splicing of BCLAF1 pre-mRNA appears to be a major contributor to colon cancer development ( Zhou et al. 2014 ). BCLAF1 may play a role in establishing senescence in response to DNA damage ( Shao et al. 2016 ). Recently, a function of BCLAF1 in antiviral immunity has been suggested through IFN signaling ( Qin et al. 2019 ).

Storage Information
This product is shipped at ambient temperature.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles