| Fiber ID | 0.5mm |
|---|---|
| Length | 30cm (EFA: 236 cm²) |
| MWCO | 750 kDa |
| Filter Format | Lab Hollow Fiber |
|---|---|
| Scale | Lab Scale, Process Development |
| Fiber ID | 0.5 mm and 1.0 mm |
| Flow Path | 30 cm (ODxLength: 1.3 * 34.8 cm) 60 cm (ODxLength: 1.6 * 64.8 cm) |
| MWCO | 3/ 5/ 10/ 30/ 50/ 100/ 300/ 500/ 750 kDa |
| Typical Application | E. coli concentration, E. coli homogenate clarification (750 kDa / 0.22 μm) Insulin protein crystallization (0.45 μm) LNP/Exosome concentration and clarification (100/ 300 kDa) |
|---|
| Membrane Material | Modified Polyethersulfone (mPES) |
|---|---|
| Housing Material | Polysulfone |
| Seals (internal) | Epoxy Resin |
| Feed/Retentate Port | 0.5" TC (compatible with 3/4" TC fitting) |
|---|---|
| Permeate Port | 3/16" HB |
Answer:750 kDa nominal MWCO.
Answer:The fibers have 0.5 mm internal diameter and 30 cm effective length, with approximately 236 cm² membrane area.
Answer:Yes. It is a reusable nonsterile mPES hollow fiber module that requires suitable cleaning and sanitization procedures.
The Biophsep Lab hollow fiber module provides reusable tangential-flow filtration for laboratory clarification and molecular-size-based separation experiments. Its modified polyethersulfone membrane has a 750 kDa nominal molecular weight cut-off, with 0.5 mm fiber internal diameter and 30 cm effective fiber length. This Lab configuration provides approximately 236 cm² of membrane area and uses a compact fiber bundle for small-volume process development. Tangential flow helps limit surface cake buildup by moving feed parallel to the membrane while collecting filtrate through the fiber wall. A high cut-off can support clarification of bacterial homogenates and passage of smaller soluble proteins, but recovery depends on product size, aggregation and feed composition. Optimize crossflow, transmembrane pressure and sample pretreatment with representative material. The module is supplied nonsterile and supports cleaning and reuse under an appropriate validated sanitation procedure; it is not a sterilizing filter.
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| Compliance | USP <788> Particulate Matter USP <87> Cytotoxicity USP <88> Biological Reactivity FDA Indirect Food Additives, 21 CFR 177-182 ADCF Materials |
|---|---|
| Bacterial Endotoxin | Endotoxin Limit of WFI System<0.25 EU/mL with the Limulus Amebocyte Lysate (LAL), USP <85> |
| Reusable | Yes |
|---|---|
| Pre-use Treatment | NaOH Sanitization for Pyrogen Removal |
| Sterility | Non-sterile |
| Pack Size | Pack of 1 |
|---|---|
| Packaging | Individually packed in a double PE bag |