| Fiber ID | 0.5mm |
|---|---|
| Length | 30cm (EFA: 118 cm²) |
| MWCO | 300 kDa |
| Filter Format | MiniLab Hollow Fiber |
|---|---|
| Scale | Lab Scale, Process Development |
| Fiber ID | 0.5 mm and 1.0 mm |
| Flow Path | 30 cm (ODxLength: 1 * 34.6 cm) 60 cm (ODxLength: 1 * 64.6 cm) |
| MWCO | 3/ 5/ 10/ 30/ 50/ 100/ 300/ 500/ 750 kDa |
| Typical Application | E. coli concentration, E. coli homogenate clarification (750 kDa / 0.22 μm) Insulin protein crystallization (0.45 μm) LNP/Exosome concentration and clarification (100/ 300 kDa) |
|---|
| Membrane Material | Modified Polyethersulfone (mPES) |
|---|---|
| Housing Material | Polysulfone |
| Seals (internal) | Epoxy Resin |
| Feed/Retentate Port | Female Luer Lock |
|---|---|
| Permeate Port | Female Luer lock |
Answer:A nominal 300 kDa MWCO modified polyethersulfone hollow fiber membrane.
Answer:0.5 mm inner diameter, 30 cm effective length and 118 cm² membrane area.
Answer:Tangential flow ultrafiltration for concentration, separation and diafiltration.
The Cobetter Biophsep MiniLab hollow fiber module is a tangential flow ultrafiltration device built with modified polyethersulfone membrane fibers. This configuration uses 0.5 mm fiber lumens, a 30 cm effective fiber length and a nominal 300 kDa molecular-weight cutoff. Its effective filtration area is 118 cm², making it suitable for small-scale process development and concentration or diafiltration of appropriately sized biological particles and macromolecular assemblies. Tangential feed circulation creates retentate and permeate streams while limiting direct accumulation at the membrane surface compared with dead-end filtration. The 300 kDa cutoff is particularly relevant when separating larger species from lower-molecular-weight solutes; observed retention depends on molecular shape, interactions and process conditions. Female Luer-lock ports allow integration into compatible laboratory tubing assemblies. It is a hollow fiber filtration module, not a packed chromatography cartridge or sterile terminal filter. Establish feed compatibility, membrane integrity and cleaning or reuse requirements for the intended workflow.
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| Compliance | USP <788> Particulate Matter USP <87> Cytotoxicity USP <88> Biological Reactivity FDA Indirect Food Additives, 21 CFR 177-182 ADCF Materials |
|---|---|
| Bacterial Endotoxin | Endotoxin Limit of WFI System<0.25 EU/mL with the Limulus Amebocyte Lysate (LAL), USP <85> |
| Reusable | Yes |
|---|---|
| Pre-use Treatment | NaOH Sanitization for Pyrogen Removal |
| Sterility | Non-sterile |
| Pack Size | Pack of 1 |
|---|---|
| Packaging | Individually packed in a double PE bag |