Lonza, CC-7014, AoAF – Human Aortic Adventitial Fibroblasts

Product Overview Human Cardiac-Related Fibroblasts include Aortic Adventitial Fibroblasts (AoAF) isolated from the tunica external of the ascending or descending aorta and cardiac fibroblasts (NHCF-A and-V) isolated from the atrium or ventricle. Cells are isolated from normal, adult heart tissue. Cryopreserved cells are shipped at passage 2. Clonetics TM NHCF-V & -A are guaranteed through 5 population doublings and express ≥90% collagen I and ≤10% Von Willibrand factor VIII after thaw. Clonetics TM AoAF are guaranteed through 10 population doublings and are negative for alpha smooth muscle actin. All cells test negative for mycoplasma, bacteria, yeast and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis (CoA) is provided for each cell lot purchased. Request More Info
Applications Vascular diseases Neointimal formation Vascular remodeling Atherosclerosis Hypertension Myocardial repair Extracellular maintenance during cardiac cell / tissue growth Cardiac Fibrosis Paracrine signalling Toxicology Gene expression
Storage and Content 1 x Cryopreserved Ampule with ≥500,000 cells/vial