Description
Product Overview Silensomes TM are validated human pooled liver microsomes (HLM) chemically and irreversibly inactivated for one specific CYP using mechanism based inhibitors (MBI). Contents of the CYP Phenotyping Kit include 7 individual Silensomes TM HLM inhibited for CYP2C9, CYP1A2, CYP2B6, CYP2A6, CYP2D6, CYP2C8, and CYP3A4 P450s, plus the Silensomes TM Master Control. Format: Each specific CYP Silensomes TM HLM is supplied in 150 μL as 20mg/mL microsomal protein with matched Control Silensome TM HLM (batch dependent) that was treated under the exact same conditions without inhibitor. Request More Info
Benefits Minimal off target effects Directly quantitative P450 reaction phenotyping Prevalidated for minimal user effort Ready to use Applications Cytochrome P450 reaction phenotyping
Storage and Content 1 x Silensomes TM CYP3A4 HLM 1 x Silensomes TM CYP1A2 HLM 1 x Silensomes TM CYP2A6 HLM 1 x Silensomes TM CYP2B6 HLM 1 x Silensomes TM CYP2D6 HLM 1 x Silensomes TM CYP2C8 HLM 1 x Silensomes TM CYP2C9 HLM 1 x Master Control Silensomes TM HLM
