Merck, 229075-1G, 1,8-Dihydroxy-3-methylanthraquinone

Name: 1,8-Dihydroxy-3-methylanthraquinone
Brand: Merck
SKU: 229075-1G

Size:1 g, 3-Methylchrysazin, Chrysophanic acid, 98%

Available Catalog Numbers

229075-1G 229075-50MG

Catalog Number: 229075-1G

Pricing

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Category

Antibiotics & Antimycotics

Pack Size1 g

TagsChemistry & Biochemicals Biochemicals Antibiotics

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

Application
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells . It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro .
Biochem/physiol Actions
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway . Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus .
Other Notes
Keep container tightly closed in a dry and well-ventilated place.

Specifications

General

UNSPSC Code	51102829
NACRES	NA.85
PubChem Substance ID	57648009
EC Number	207-572-2
Beilstein/REAXYS Number	1252300
MDL number	MFCD00001208
InChI key	LQGUBLBATBMXHT-UHFFFAOYSA-N
InChI	1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
SMILES string	Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
assay	98%
form	crystalline
color	yellow-orange
solubility	chloroform: 1%
antibiotic activity spectrum	neoplastics
mode of action	enzyme \| inhibits
Quality Level	100
Gene Information	human ... ELA2(1991)

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