Merck, 521418-10G, 4-Cyanophenylboronic acid

Application
Reactant involved in:
Oxidative hydroxylation
Trifluoromethylation
1,4-Addition reactions

Precursor in the synthesis of inhibitors such as:
Tpl2 kinase inhibitors
P2X7 antagonists used in the treatment of pain

4-Cyanophenylboronic acid can be used as a reactant in:
Palladium-catalyzed Suzuki-Miyaura cross-coupling in water.
Ruthenium catalyzed direct arylation of benzylic sp³ carbons of acyclic amines with arylboronates.
Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids.
Ferric perchlorate-promoted reaction of fullerenes with various arylboronic acids to give fullerenyl boronic esters.
Phosphine-free Suzuki-Miyaura cross-coupling.
Palladacycles as effective catalysts for multicomponent reaction with allylpalladium-intermediates.
Chan-Lam-type Cu-catalyzed S-arylation of thiols.
Regioselective cross-coupling reactions under modfied Suzuki and Still cross-coupling reactions with copper catalysis.
Metal-free biaryl coupling reaction in the presence of dimethyl carbonate as a solvent.
Suzuki-type cross-coupling reaction with pentavalent triarylantimony diacetates in the absence of a base.

It can also be used to prepare:
Himbacine analogs as thrombin receptor antagonists and potential antiplatelet agents.
Trisulfonated calixarene upper-rim sulfonamido and their complexation with trimethyllysine epigenetic mark.
Antimalarial compounds via Suzuki cross-coupling.
Deoxyuridine derivatives.

Other Notes
Contains varying amounts of anhydride