Merck, 700039P-1MG, 24(S),25-epoxycholesterol

Name: 24(S),25-epoxycholesterol
Brand: Merck
SKU: 700039P-1MG

Size:1 mg, (24S, 25)-Epoxycholesterol, (3β, 24S)-24, 25-Epoxycholest-5-en-3-ol, Avanti Research™ - A Croda Brand

Available Catalog Numbers

700039P-1MG 700039P-5MG

Catalog Number: 700039P-1MG

Pricing

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Category

Dry Ice

Pack Size1 mg

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
24(S),25-epoxycholesterol is an oxysterol, which is produced by fibroblasts, macrophages and brain cells.
24(S),25-epoxycholesterol is a cholesterol-derived oxysterol, which is produced by fibroblasts, macrophages, and the brain cells. 24(S),25-epoxycholesterol is synthesized de novo in the mevalonate pathway.
Application
24(S),25-epoxycholesterol has been used as an oxysterol/internalstandard to study the effects of AY9944-induced changes in neurospheres.
Biochem/physiol Actions
Exogenous addition of 24(S),25-epoxycholesterol lowers 3-hydroxy-3-methylglutaryl-Coenzyme A (HMG-CoA) reductase activity, represses sterol regulatory element-binding protein (SREBP) processing, and induces liver × receptor (LXR) -gene targets in vitro.
Packaging
5 mL Amber Glass Screw Cap Vial (700039P-1mg)
5 mL Amber Glass Screw Cap Vial (700039P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

MDL number	MFCD03695562
UNSPSC Code	12352211
NACRES	NA.25
SMILES string	O1[C@H](C1(C)C)CC[C@H]([C@@H]2[C@@]3([C@H]([C@H]4[C@@H]([C@]5(CC[C@@H](CC5=CC4)O)C)CC3)CC2)C)C
InChI	1S/C27H44O2/c1-17(6-11-24-25(2,3)29-24)21-9-10-22-20-8-7-18-16-19(28)12-14-26(18,4)23(20)13-15-27(21,22)5/h7,17,19-24,28H,6,8-16H2,1-5H3/t17-,19+,20+,21-,22+,23+,24+,26+,27-/m1/s1
InChI key	OSENKJZWYQXHBN-XVYZBDJZSA-N
assay	>99% (TLC)
form	powder
packaging	pkg of 1 × 1 mg (700039P-1mg)
manufacturer/tradename	Avanti Research™ - A Croda Brand
shipped in	dry ice
storage temp.	−20°C

Ordering

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