Merck, 700149P-10MG, 16:0 cholesteryl-d7 ester

General description
Cholesteryl palmitate is a cholesteryl ester. 16:0 cholesteryl-d7 ester is the deuterated form of cholesteryl palmitate or 16:0 cholesteryl ester.
Application
16:0 cholesteryl-d7 ester has been used:
in plasma sample preparation for tandem mass spectrometry analysis (MS/MS)
as an internal standard in mass spectrometry for quantification of nerve lipids from mice
as an internal standard in time-of-flight mass spectrometry (TOFMS) for the quantification of serum extracellular vesicles (EVs) lipids
as an external calibrator and internal spiking standard in tandem mass spectroscopy measurements
in liposome preparation for retinyl ester hydrolase (REH) and cholesteryl esterase activity assay

Biochem/physiol Actions
Cholesteryl palmitate is associated with atherosclerotic plaque. Deuterated cholesteryl palmitate in used in reconstituting high-density lipoprotein (HDL). An elevated levels of the ratio of cholesteryl oleate to cholesteryl palmitate is implicated with apoptotic cell death in the atherosclerotic lesions.
Packaging
5 mL Amber Glass Screw Cap Vial (700149P-10mg)
5 mL Amber Glass Screw Cap Vial (700149P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC