Merck, 810250C-1MG, 25-NBD Cholesterol

Name: 25-NBD Cholesterol
Brand: Merck
SKU: 810250C-1MG

Size:1 mg, 25-[N-[(7-nitro-2-1, 3-benzoxadiazol-4-yl)methyl]amino]-27-norcholesterol, Avanti Research™ - A Croda Brand 810250C

Available Catalog Numbers

810250C-1MG 810250C-5MG

Catalog Number: 810250C-1MG

Pricing

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Category

Dry Ice

Pack Size1 mg

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
25-NBD Cholesterol is a fluorescent derivative of cholesterol. Its fluorescent property is due to presence of NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) group.
Application
25-NBD Cholesterol can be used as a labeling agent for confocal microscopy in studying endosomal trafficking and vesicle formation.
Biochem/physiol Actions
Cholesterol is synthesized via a cascade of enzymatic reactions known as the mevalonate pathway. Cholesterol plays a major role in the architecture and stability of the plasma membrane and is also involved in the synthesis of cholecalciferol (Vitamin D3). Cholesterol build up on the walls or arteries causes obstruction of blood flow leading to a serious condition called artherosclerosis. It is a precursor for bile acid and for the synthesis of steroid hormones like progesterone, testosterone, cortisol, and aldosterone.
Packaging
5 mL Clear Glass Sealed Ampule (810250C-10mg)
5 mL Clear Glass Sealed Ampule (810250C-1mg)
5 mL Clear Glass Sealed Ampule (810250C-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

MDL number	MFCD22416768
UNSPSC Code	12352211
NACRES	NA.25
Web Name Suffix Override	Avanti Research™ - A Croda Brand
SMILES string	[N+](=O)([O-])c1c2n[o]nc2c(cc1)N(C(CCC[C@H]([C@H]3[C@@]4([C@H]([C@H]5[C@@H]([C@]6(CC[C@@H](CC6=CC5)O)C)CC4)CC3)C)C)C)C
InChI	1S/C33H48N4O4/c1-20(7-6-8-21(2)36(5)28-13-14-29(37(39)40)31-30(28)34-41-35-31)25-11-12-26-24-10-9-22-19-23(38)15-17-32(22,3)27(24)16-18-33(25,26)4/h9,13-14,20-21,23-27,38H,6-8,10-12,15-19H2,1-5H3/t20-,21?,23+,24+,25+,26+,27+,32+,33-/m1/s1
InChI key	RMGLSQAGXRZCPZ-OVHOIDCTSA-N
assay	>99% (TLC)
form	liquid
packaging	pkg of 1 × 1 mL (810250C-10mg)
manufacturer/tradename	Avanti Research™ - A Croda Brand 810250C
concentration	1 mg/mL (810250C-1mg)
shipped in	dry ice
storage temp.	−20°C

Ordering

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