Merck, 850104P-100UG, 18:0 Lyso PI

Name: 18:0 Lyso PI
Brand: Merck
SKU: 850104P-100UG

Size:100 μg, 1-octadecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); PI(18:0/0:0); 110719, 1-stearoyl-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt), powder

Available Catalog Numbers

850104P-100UG 850104P-500UG

Catalog Number: 850104P-100UG

Pricing

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Category

Dry Ice

Pack Size100 µg

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Lysophosphatidylinositol (LPI), an acidic lysophosholipid, carries inositol in its head group.
Application
18:0 Lyso PI (1-stearoyl-2-hydroxy-sn-glycero-3-phosphoinositol) has been used as lysophosphatidylinositol (LPI) substrate in lysophosphatidylinositol acyltransferase biochemical assay to determine lyso-phosphatidylinositol acyltransferase (LPIAT) activity of liver microsomes. It may be used as a synthetic LPI to compare its effects with liver LPI in transferrin (Tf) endocytosis. It may also be used as LPI standard to quantify serum LPI levels in gonadectomized rats.
Biochem/physiol Actions
Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.
Lysophosphatidylinositol (LPI) displays mitogenic activity and can serve as a bioactive lysophospholipid mediator. It may be considered as a lipid mediator.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (850104P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850104P-500ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

UNSPSC Code	51191904
NACRES	NA.25
Web Name Suffix Override	Avanti Research™ - A Croda Brand
InChI	1S/C27H53O12P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(29)37-18-20(28)19-38-40(35,36)39-27-25(33)23(31)22(30)24(32)26(27)34;/h20,22-28,30-34H,2-19H2,1H3,(H,35,36);1H3/t20-,22-,23-,24+,25-,26-,27-;/m1./s1
InChI key	QVEDYTZLCBLSCH-FJYNCLFYSA-N
SMILES string	[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]
assay	>99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)
form	powder
packaging	pkg of 1 × 100 μg (with stopper and crimp cap (850104P-100ug))
manufacturer/tradename	Avanti Research™ - A Croda Brand 850104P
lipid type	phosphoglycerides
shipped in	dry ice
storage temp.	−20°C

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