Merck, 861650-100MG, (+)-Biotin 4-nitrophenyl ester

Name: (+)-Biotin 4-nitrophenyl ester
Brand: Merck
SKU: 861650-100MG

Size:100 mg, 4-Nitrophenyl (+)-biotinate, d-Biotin p-nitrophenyl ester, BNP, 98%

Catalog Number: 861650-100MG

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Category

Heterogeneous Catalysts

Pack Size100 mg

TagsCatalysts Chemistry & Biochemicals Chiral Catalysts & Ligands

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

Application
(+)-Biotin 4-nitrophenyl ester may be used in the preparation of biotin tagged ARC (adenosine-oligoarginine conjugate) derivative during cellular protein uptake studies. It may also be used to prepare biotinylated quinazoline derivatives, which shows inhibitory activities against VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinase. (+)-Biotin 4-nitrophenyl ester undergoes hydrolysis in the presence of Na[¹⁷O]H to form [¹⁷O₂]biotin, which can be used in solid-state ¹⁷O NMR spectroscopic experiments to analyze large protein-ligand complexes.

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Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.

Specifications

General

UNSPSC Code	12352108
NACRES	NA.22
PubChem Substance ID	24888552
MDL number	MFCD15141972
Beilstein/REAXYS Number	5795805
InChI key	YUDNXDTXQPYKCA-YDHLFZDLSA-N
SMILES string	[O-][N+](=O)c1ccc(OC(=O)CCCC[C@@H]2SCC3NC(=O)NC23)cc1
InChI	1S/C16H19N3O5S/c20-14(24-11-7-5-10(6-8-11)19(22)23)4-2-1-3-13-15-12(9-25-13)17-16(21)18-15/h5-8,12-13,15H,1-4,9H2,(H2,17,18,21)/t12-,13-,15-/m0/s1
assay	98%
form	powder
optical activity	[α]25/D +51°, c = 2 in DMF: AcOH (99:1)
mp	163-165 °C (lit.)
solubility	methanol: 25 mg/mL, clear, colorless to greenish-yellow
functional group	ester

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