Merck, A9730-100MG, Adefovir dipivoxil

Name: Adefovir dipivoxil
Brand: Merck
SKU: A9730-100MG

Size:100 mg, 9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine

Available Catalog Numbers

A9730-100MG A9730-50MG

Catalog Number: A9730-100MG

Pricing

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Category

Antibiotics & Antimycotics

Pack Size100 mg

TagsChemistry & Biochemicals Biochemicals Antibiotics

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

Biochem/physiol Actions
Adefovir is an antiviral acyclic nucleoside phosphonate (ANP) analog that works by blocking reverse transcriptase. It is an inhibitor of duck hepatitis B virus (DHBV) replication that inhibits covalently closed circular DNA (CCC DNA) amplification. Cytotxicity is induced by Human Renal Organic Anion Transporter 1 (hOAT1). Adefovir is an Inhibitor of edema factor (EF)-induced cAMP accumulation and changes in cytokine production in mouse primary macrophages .
Other Notes
Keep container tightly closed in a dry and well-ventilated place.

Specifications

General

NACRES	NA.76
PubChem Substance ID	329771057
UNSPSC Code	51102829
MDL number	MFCD00869897
InChI key	WOZSCQDILHKSGG-UHFFFAOYSA-N
SMILES string	CC(C)(C)C(=O)OCOP(=O)(COCCn1cnc2c(N)ncnc12)OCOC(=O)C(C)(C)C
InChI	1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23)
biological source	synthetic
assay	≥98% (HPLC)
form	powder
solubility	ethanol: 50 mg/mL
antibiotic activity spectrum	viruses
mode of action	enzyme \| inhibits
storage temp.	−20°C
Quality Level	100

Ordering

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