Merck, U3750-25G, Uridine

Name: Uridine
Brand: Merck
SKU: U3750-25G

Size:25 g, 1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside, ≥99%

Available Catalog Numbers

U3750-100G U3750-1G U3750-25G

Catalog Number: U3750-25G

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Category

Nucleotides & Nucleosides

Pack Size25 g

TagsChemistry & Biochemicals Biochemicals Nucleosides & Nucleotides

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is synthesized in living organisms by de novo and salvage pathways.
Application
Uridine has been used:
as a component of hippocampal neuron medium for culture of primary hippocampal neuron cells
in uridine rescue experiments in mouse embryonic fibroblasts and human breast cancer cells
in chase sequencing experiments

Biochem/physiol Actions
Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.

Specifications

General

Web Name Suffix Override	≥99%, synthetic (organic), powder
NACRES	NA.51
PubChem Substance ID	24900640
UNSPSC Code	41106305
EC Number	200-407-5
MDL number	MFCD00006526
Beilstein/REAXYS Number	754902
InChI key	DRTQHJPVMGBUCF-XVFCMESISA-N
InChI	1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
SMILES string	OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
biological source	synthetic (organic)
assay	≥99%
form	powder
Quality Level	200
Gene Information	mouse ... Uck1(22245)
mp	163-167 °C (lit.)
solubility	H2O: 50 mg/mL, clear, colorless

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