Miltenyi, 170-076-508, MACS® GMP CD62L-PE

Name: MACS® GMP CD62L-PE
Brand: Miltenyi
SKU: 170-076-508

Size:5 mL

Catalog Number: 170-076-508

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Category

Fluorescent-Conjugated Antibodies for FACS

Pack Size5 mL

TagsCell manufacturing platform MACS GMP Portfolio MACS GMP Cell Labeling Reagents

Description

Background information
Clone 145/15 recognizes the human CD62L antigen. Most hematopoietic cells express CD62L, including many peripheral blood B cells, T cells, monocytes, granulocytes, and some myeloid cells from bone marrow, and thymocytes. CD62L is continuously cleaved from the cell surface of neutrophils and lymphocytes by endoproteases. CD62L is important for homing of naive lymphocytes via endothelial venules to peripheral lymph nodes and Peyer’s patches.

Applications
MACS® GMP CD62L Fluorescent Antibodies are for identification of CD62L-positive cells by flow cytometry as well as cell enrichment by flow cytometric sorting.

Quality statement
MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

Disclaimer
MACS GMP Products are for ex vivo cell processing only, and are not intended for human in vivo applications. For regulatory status in the USA, please contact your local representative.

Overview
MACS® GMP CD62L Fluorescent Antibodies consist of a mouse monoclonal antibody against the human CD62L antigen conjugated to a fluorochrome. They are developed for flow cytometric identification and flow cytometric sorting of CD62L-positive cells.

Specifications

General

Clone	145.15.3.8C12
Isotype	mouse IgG1κ
RRID	AB_2802077

FAQs

Question: Which marker does the antibody target?

Answer:It recognizes human CD62L, also known as L-selectin.

Question: Which fluorescent tag is supplied?

Answer:The antibody is conjugated to phycoerythrin (PE).

Question: What is its package size?

Answer:The configuration provides 5 mL of reagent.

Application Note

Miltenyi MACS GMP CD62L-PE is a phycoerythrin-conjugated antibody reagent for fluorescent identification and sorting of human leukocyte populations expressing CD62L. CD62L, also called L-selectin, participates in leukocyte trafficking and is frequently used with CD45RA, CD45RO and other markers to distinguish lymphocyte differentiation states. The PE label supports detection using a compatible flow cytometer or cell sorter equipped for phycoerythrin fluorescence. This 5 mL configuration is intended for controlled ex vivo cell processing workflows, including immunophenotypic analysis and selection of defined T-cell subsets. Staining results depend on antigen expression, sample preparation and the design of the complete antibody panel. This reagent binds CD62L and is not interchangeable with the CD45RA-FITC or CD25-PE-biotin variants in the MACS GMP fluorescent antibody range.

Ordering

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