Proteintech, 98051-1-RR, Anti-Human CD138/Syndecan-1 Rabbit Recombinant Antibody

98051-1-RR targets CD138/Syndecan-1 in IHC, FC applications and shows reactivity with human samples.
Tested Applications
Positive IHC detected in: human tonsillitis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Positive FC detected in: U266 cells
Recommended dilution
Immunohistochemistry (IHC): IHC : 1:500-1:2000
Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension
Background Information
CD138, also named as Syndecan-1 (SDC1), is an integral membrane protein. It participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a heparan sulfate proteoglycan expressed on the surface of, and actively shed by, myeloma cells. Altered syndecan-1 expression has been detected in several different tumor types. CD138 was regarded as a useful marker for labeling normal and neoplastic plasma cells and plasmacytoid lymphomas.