Description
98146-1-RR targets CD157 in FC applications and shows reactivity with human samples.
Tested Applications
Positive FC detected in: human peripheral blood leukocytes
Recommended dilution
Flow Cytometry (FC): FC : 0.15 ug per 10^6 cells in 100 μl suspension
Background Information
CD157, also known as bone marrow stromal cell antigen 1 (BST-1), or ADP-ribosyl cyclase 2, is a glycosyl phosphotidylinositol-anchored protein that stimulates pre-B-cell growth and has adenosine diphosphate (ADP)-ribosyl cyclase and cyclic ADP-ribose (cADPR) hydrolase activity (PMID: 9473467, 11866528). The two enzymatic activities are responsible for the synthesis and hydrolysis of cADPR, a novel second messenger of calcium release from intracellular calcium stores.