Proteintech, 98579-2-RR, Anti-Human CD1b Rabbit Recombinant Antibody

98579-2-RR targets CD1b in FC applications and shows reactivity with human samples.
Tested Applications
Positive FC detected in: human monocyte-derived mature dendritic cells, MOLT-4 cells
Recommended dilution
Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension
Background Information
CD1b is a ~45 kDa transmembrane glycoprotein that belongs to the MHC class I-like CD1 family. It associates non-covalently with β2-microglobulin to form a functional antigen-presenting heterodimer. CD1b is expressed on cortical thymocytes, dendritic cells (PMID: 17593659). It has the capacity to bind self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on T cells (PMID: 30399491).