Proteintech, 98643-1-RR, Anti-Human CD1a Rabbit Recombinant Antibody

98643-1-RR targets CD1a in FC applications and shows reactivity with human samples.
Tested Applications
Positive FC detected in: MOLT-4 cells, FC receptor blocked human monocyte-derived mature dendritic cells
Recommended dilution
Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension
Background Information
CD1a is an antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes, before trafficking back to the cell surface.