Proteintech, 98701-3-RR, Anti-Canine IL-2 Rabbit Recombinant Antibody

98701-3-RR targets IL-2 in FC (Intra) applications and shows reactivity with canine samples.
Tested Applications
Positive FC (Intra) detected in: Transfected CHO-K1 cells
Recommended dilution
Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension
Background Information
Interleukin-2 (IL-2) is a four-helix bundle, type I cytokine that functions as a growth factor for a wide range of leukocytes. In the immune system, IL-2 is essential for immune homeostasis, normal T regulatory cell function, and self-tolerance. It regulates immune cell homeostasis and has been used to treat a range of disorders including cancer and autoimmune disease. IL-2 signals through heterodimerization of the IL-2Rβ and IL-2Rγ receptor subunits (PMID: 25992858, 24907378, 15034008, 17981641).