Description
CMM HyperCel resin is composed of a rigid cellulose matrix that has flow properties compatible with the needs of manufacturing scale protein production.
The proprietary ligand, containing both a primary amine and a carboxyl group, confers cation exchange and hydrophobicity properties to the chromatography resin. The flexibility of the ligand enables the separation of proteins with a large variety of isoelectric points and hydrophobicity levels, and multiple conditions can be employed to separate targeted molecules from contaminants.
CMM HyperCel pre-packed columns are designed to simplify resin screening and selection, making them ideal for optimizing process steps. The RoboColumn®format is particularly suited for high throughput process development (HTPD), allowing for efficient and streamlined purification processes. Features and Benefits Unique selectivity
High capacity mixed mode chromatography resin
High recovery, low elution volume
Easy CIP, NaOH stable Applications Capture of mAbs, Fab fragments and recombinant proteins from challenging feedstocks
Separation of proteins with similar isoelectric point and | or hydrophobicity at low or high conductivity
