Description
Quadrupole time-of-flight for biologics
Standardized biologics characterization workflows have never been easier
Built specifically for biologics characterization, the X500B QTOF system will help you boost your analytical capacity, simplify workflows and accelerate throughput in a matter of days. This high-resolution quadrupole time-of-flight (QTOF) system combines robust and reliable instrumentation with powerful and intuitive software to get you to characterization answers faster and easier, in a true benchtop platform. And with tools to enable a complete multiple attribute methodology (MAM) workflow, to allow you to define, track and quantify product quality attributes as well as specified contaminants, or find new unspecified impurities in a single software solution.
Key Features
Novel N-optic TOF design gives optimal mass accuracy and resolution, even for large biotherapeutics such as mAbs and antibody drug conjugates
Renowned Turbo V ion source provides efficient ion production while limiting contamination for maximized robustness and uptime
Purpose built for biologics characterization and engineered with ease-of-use and simplicity in mind to accelerate and streamline biotherapeutic analysis
Perform intact mass, subunit analysis, and peptide mapping characterization on this single, true benchtop system
Achieve clarity on your biotherapeutic
Leveraging the latest acquisition techniques and built on a heritage of proven performance, Biologics Explorer software delivers highly accurate and informative workflows for fully characterizing protein biotherapeutics.
Boost lab productivity
Designed especially for robustness and reliability, the X500B QTOF system gives you reproducible biologics results with maximum system uptime. From the front end all the way through the TOF path, see how the X500B system is built for reliability.
A compact workhorse
The true benchtop stature of the X500B QTOF system occupies less of your valuable lab space than any other high resolution mass spectrometry system on the market today. See what gives this benchtop system the performance edge.
Easy to learn, compact and robust
Size
A compact true benchtop system, with an ambidextrous dress panel to easily fit in your available space
Ionization source
Renowned, SCIEX Turbo V ion source for maximum robustness
Calibration
Automated on-board calibration and dual-spray source gives worry free acquisition
Maintenance
Easy Qjet ion guide access for straightforward maintenance
Operating system
The SCIEX OS software user interface is incredibly easy to learn and maintain
Mass accuracy
Heated TOF path eliminates environmental temperature impact
Data processing Software
Biologics Explorer software delivers data visualization and automated calculations for intact, subunit, and peptide level analyses
Purpose-built for biologics characterization
The first high resolution QTOF specifically for biologics
The X500B QTOF system was designed from the ground up to accelerate everyday biologics characterization workflows.
Intact mass analysis
Answers, simple and streamlined Solutions for biotherapeutic intact mass analysis that gives you better information for better biologics decisions
Peptide mapping
Simple solutions to complex workflows Comprehensive biotherapeutic peptide mapping workflows for better information, faster
Antibody-drug conjugates (ADC)
DAR, demystified, Learn how to focus on moving your antibody drug conjugate (ADC) through development
Lot comparability
Compare it and share it Easily identify differences from lot-to-lot, even with large data sets
Multiple attribute methodology (MAM)
Implement a complete solution for MAM to streamline biotherapeutic analysis and purity testing throughout development
More than just a mass spec
The X500B QTOF system is a complete solution for biologics characterization. The X500B provides a complete solution, designed to elevate your biologics characterization to a whole new level of productivity.
ExionLC 2.0 and 2.0+ system
A perfect match for the X500B QTOF system, delivering reliability and repeatability.
SCIEX OS software
Our newest operating platform, built for remarkable simplicity and productivity.
Biologics Explorer software
Reach decisions on the most important critical quality attributes for biopharmaceuticals faster and more confidently.
