Thermo Fisher, 1033270500, CaptureSelect™ LC-kappa (Human) Affinity Ligand

Quantity: 500 μg
Unit Size: Each
As described by Ereño-Orbea et. al. (1), this affinity ligand can be used as a crystallization chaperone to enhance the crystallization probability of human Fab fragments and assist in antibody structure determinations.Free of animal componentsCaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).1. Ereño-Orbea J, Sicard T, Cui H, Carson J, Hermans P, Julien JP. Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments. J Mol Biol. 2018 430(3):322-336.