Thermo Fisher, 2943752050, CaptureSelect™ LambdaXP Affinity Matrix

Name: CaptureSelect™ LambdaXP Affinity Matrix
Brand: Thermo Fisher
SKU: 2943752050

Quantity: 50 mL, Unit Size: Each, CaptureSelect LambdaXP Affinity Matrix was specifically designed for the purification of recombinant human immunoglobulins and Fab fragments containing a lambda light chain. The ligand binds to the constant domain of the human lambda light chain and recognizes all isotypes including IgA, IgM, IgD, and IgE.

Catalog Number: 2943752050

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Category

Affinity Tag Purification Resins

Pack Size50 mL

TagsProtein Purification Protein Analysis Reagents Protein Purification Reagents and Kits

CollectionsThermo Fisher Protein Analysis Reagents for Western Blot, ELISA & Proteomics Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 50 mL
Unit Size: Each
Features of this affinity matrix include:
• Efficient elution of Fab fragments and immunoglobulins containing a lambda light chain, no cross binding to the Fc-region or kappa light chains
• One-step purification from crude material with high purity and yield
• Excellent scalability
• Non-animal-derivedCaptureSelect LambdaXP Affinity Matrix can be utilized for the purification of human Ig's and Fab/Fab2 fragments directly from complex source materials and enables a robust and efficient purification process with excellent purity obtained in a single step.Free of animal componentsCaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).Main characteristics:
• Matrix:agarose-based, epoxide-activated
• Average particle size:65 ± 10 μm
• Ligand:CaptureSelect LambdaXP
• Ligand coupling method:epoxide coupling
• Binding capacity:>30 g IgG/L resin depending on flow rate, column height, and contact time
• Elution conditions:25 mM sodium acetate, pH 3.5
• Flow characteristics:50–200 cm/h (up to 2 bar)
• Formulation buffer:20% (v/v) ethanol

Specifications

General

Binding Capacity	>30 g IgG/L resin
Flow Rate	50 to 200 cm/hr. (Up to 2 bar)
For Use With (Application)	Lambda Fab purification
Formulation	50% slurry suspension in 20% ethanol
Ligand Type	LambdaXP
Matrix	Agarose-based, epoxide-activated
Max. Operating Pressure	2 bar
Quantity	50 mL
Shipping Condition	Ships at 2°C to 8°C
Target	Lambda light chain
Form	Agarose Bead
Particle Size	65 ±10 μm
Product Line	CaptureSelect
Type	Affinity Matrix
Unit Size	Each

Ordering

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Unless otherwise stated, the minimum order amount is USD 1,000.
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