Thermo Fisher, 2943972010, CaptureSelect™ IgA-XL Affinity Matrix

Name: CaptureSelect™ IgA-XL Affinity Matrix
Brand: Thermo Fisher
SKU: 2943972010

Quantity: 10 mL, Unit Size: Each, CaptureSelect IgA-XL Affinity Matrix is intended for the purification of human IgA, with no binding to other immunoglobulins. The IgA-XL affinity matrix provides improved binding capacities (>15 g/L IgA) and elution characteristics (full elution at pH 4) compared to CaptureSelect IgA Affinity Matrix.

Catalog Number: 2943972010

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Category

Affinity Tag Purification Resins

Pack Size10 mL

TagsProtein Purification Protein Analysis Reagents Protein Purification Reagents and Kits

CollectionsThermo Fisher Protein Analysis Reagents for Western Blot, ELISA & Proteomics Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 10 mL
Unit Size: Each
Features of this affinity matrix include:
• Purification of all IgA serotypes: IgA1, IgA2, dimeric IgA, and S-IgA (secretory IgA)
• IgA purification from plasma, serum, and recombinant sources
• Efficient purification of IgA with high yields and retained activity
• Excellent scalability
• Non-animal-derivedCaptureSelect IgA-XL Affinity Matrix binds to the Fc part of IgA. The high selectivity and yields obtained using IgA-XL Affinity Matrix enable a robust, fast, and efficient purification process with excellent purity obtained in one step.Animal origin statementCaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12–15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (animal origin-free).Main characteristics
• Matrix:agarose-based, epoxide activated
• Average particle size:65 ± 10 μm
• Ligand:CaptureSelect IgA-XL affinity ligand
• Ligand coupling method:epoxide
• Binding capacity:> 15 g/L at 5 minutes residence time, tested with plasma-derived polyclonal IgA
• Elution conditions:20 mM sodium citrate, pH 4
• Flow characteristics:50–200 cm/h (up to 2 bar)
• Formulation buffer:20% (v/v) ethanol

Specifications

General

Flow Rate	50–200 cm/hr. (up to 2 bar)
For Use With (Application)	Purification of all IgA subtypes (IgA1, IgA2, dimeric IgA, secretory IgA)
Formulation	20% (v/v) ethanol
Ligand Type	CaptureSelect IgA-XL Affinity Ligand
Quantity	10 mL
Target	IgA-Fc domain
Form	Resin Slurry
Particle Size	65 ±10 μm
Product Line	CaptureSelect
Type	Affinity Matrix
Unit Size	Each

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