Thermo Fisher, 30103-104630, Hypersil™ ODS C18 Columns

Hypersil™ ODS C18 Column, 100 x 4.6 mm, 3 µm is used for general-purpose reversed-phase HPLC separations of acidic, neutral, nonpolar, moderately polar, and lipophilic compounds. The analytical column uses an endcapped C18 stationary phase on spherical, fully porous Type A silica and is packed with 3 µm particles in a 4.6 mm inner-diameter × 100 mm format. The Hypersil Classical ODS phase has a 120 Å pore size, 170 m²/g surface area, and 10% carbon load. It operates across pH 2–8, supports temperatures up to 60 °C, and is rated to 5800 psi (400 bar). These specifications make it suitable for established HPLC procedures that use USP L1 chemistry and require a conventional C18 phase with documented reproducibility. The phase is widely used in routine analytical workflows and can separate a broad range of compounds, including lipophilic analytes such as triglycerides. The 100 mm bed length and 3 µm packing provide the exact hardware configuration needed when a validated method specifies these dimensions within the Hypersil ODS C18 family.