Thermo Fisher, 30105-124630, Hypersil™ ODS C18 Columns

Name: Hypersil™ ODS C18 Columns
Brand: Thermo Fisher
SKU: 30105-124630

Length (Metric): 125 mm, Diameter (Metric): 4.6 mm, Particle Size: 5 μm, Column Format: Analytical Column, Unit Size: Each, Choose Thermo Scientific™ Hypersil™ ODS C18 HPLC Columns for a general purpose C18 phase to use in a broad range of applications.Hypersil stationary phases are recognized as an industry standard in HPLC. Proven as an effective analytical tool, the classical Hypersil phases are well established and referenced in many HPLC methods worldwide. Quality is assured by manufacture

Catalog Number: 30105-124630

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General

Column Format	Analytical Column
Column Type	Reversed Phase
Endcapped	Yes
Max. Pressure	5800 psi (400 bar)
Packing Material	Spherical, Fully Porous Type A Silica
Stationary Phase	C18
Surface Area	170 m²/g
Temperature	60°C
USP Type	L1
Carbon Load	10%
Diameter (Metric)	4.6 mm
Length (Metric)	125 mm
Particle Size	5 μm
Phase	Reversed Phase
Pore Size	120 Å
Product Line	Hypersil Classical
pH	2 to 8
Unit Size	Each

FAQs

Question: What separation mode and stationary phase does this column use?

Answer:It is an analytical reversed-phase HPLC column using an endcapped C18 stationary phase on fully porous Type A silica.

Question: What operating limits apply to the Hypersil ODS C18 phase?

Answer:The phase supports pH 2–8, temperatures up to 60 °C, and pressures up to 5800 psi (400 bar).

Question: What are the dimensions and particle size of this specific column?

Answer:It is 4.6 mm ID × 125 mm and is packed with 5 µm particles.

Application Note

Hypersil™ ODS C18 Column, 125 x 4.6 mm, 5 µm is used for general-purpose reversed-phase HPLC separations of acidic, neutral, nonpolar, moderately polar, and lipophilic compounds. The analytical column uses an endcapped C18 stationary phase on spherical, fully porous Type A silica and is packed with 5 µm particles in a 4.6 mm inner-diameter × 125 mm format. The Hypersil Classical ODS phase has a 120 Å pore size, 170 m²/g surface area, and 10% carbon load. It operates across pH 2–8, supports temperatures up to 60 °C, and is rated to 5800 psi (400 bar). These specifications make it suitable for established HPLC procedures that use USP L1 chemistry and require a conventional C18 phase with documented reproducibility. The phase is widely used in routine analytical workflows and can separate a broad range of compounds, including lipophilic analytes such as triglycerides. The 125 mm bed length and 5 µm packing provide the exact hardware configuration needed when a validated method specifies these dimensions within the Hypersil ODS C18 family.

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