Thermo Fisher, 952504, GeneChip™ miRNA 4.0 Assay

Quantity: 30 reactions
Unit Size: Each
• Many diseases, including cancer, are frequently described as diseases of disordered gene expression
• It is estimated that more than 30% of protein translation of coding genes is regulated by miRNA
• There is also a large amount of growing evidence suggesting miRNA interacts with long non-coding RNA in the signaling networks that regulate alternative splicing events, which impacts various cellular processes
• Measuring the changes in these critical nodes of regulation is extremely important for deciphering the biological context of differentially expressed genes
• This array design is a powerful tool for studying the role of small non-coding RNAs and their involvement in a broad spectrum of developmental and physiological mechanisms
• This array offers updated content with the same high performance as the previous-generation array.
• Designed to interrogate all mature miRNA sequences in miRBase Release 20
• Analysis files contain host gene ID, predicted and validated miRNA target genes, and clustered miRNA information
• Analyze human, mouse, rat, or every miRNA for all species using the same array
• Requires as little as 130 ng total RNA