Description
Quantity: 15 mL vial
Unit Size: Each
Features of CTS Detachable Dynabeads CD4 include:
• Empower users with process flexibility by allowing active release of beads from target cells at any time
• Optimize target cell purity and yield thanks to the active release mechanism that gives users more control
• Provide an automation-friendly solution by working directly with the CTS DynaCellect Magnetic Separation System
• Enable consistent performance in light of biological variability within the starting material
• Suitable for both autologous and allogeneic cell therapy manufacturing processesThese Detachable Dynabeads are intended for use with CTS Detachable Dynabeads Release Buffer, which has an active ingredient, biotin, that competitively displaces a biotin derivative on the surface of the beads. This proprietary mechanism allows users to achieve active release of the beads from target cells at any time within their process.Based on a recommended 4-to-1 bead-to-target-cell ratio (not total nucleated cell number), one 15 mL vial can theoretically isolate up to 1.5 x 10^9 CD4+ T cells.CTS Detachable Dynabeads also include a Drug Master File (DMF) to support cross-referencing in regulatory submissions prior to clinical trial and commercial manufacturing use.
